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Hyaluronsure (HA) und das abbauende Enzym Hyaluronidase (HAase) sind direkt mit der Blasentumorangiogenese und Metastasierung verbunden. Anhand von 513 Urinproben und 83 Gewebeproben untersuchten wir die Genauigkeit von HA und HAase, Blasenkarzinome zu entdecken. Erhhte HA-Urinwerte (500 ng/ml) sprachen fr ein Blasenkarzinom unabhngig vom Tumorgrad. Erhhte HAase-Urinwerte (10 mU/mg) sprachen fr einen...
Calreticulin (CR) is a Ca 2+ -binding, multifunctional protein. The amazing array of CR-associated functions range from intracellular activities in secondary messenger release, protein folding and the modulation of gene expression to potential interactions with host receptors and signaling machinery and recognition by the host immune system. The multifunctional nature of CR may impact...
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