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Inhibition of influenza A virus infection by multivalent sialic acid inhibitors preventing viral hemagglutinin binding to host cells of the respiratory tract is a promising strategy. However, optimal geometry and optimal ligand presentation on multivalent scaffolds for efficient inhibition both in vitro and in vivo application are still unclear. Here, by comparing linear and dendritic polyglycerol...
We describe the interfacial self-assembly of nanoparticles at liquid–liquid interfaces and in block copolymers. At the interface of two immiscible liquids, the particles assemble into disordered but densely packed monolayers. This self-assembly process was investigated ex situ with scanning force microscopy (SFM) and transmission electron microscopy (TEM), and laser scanning confocal microscopy (LCSM)...
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