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Alkali-labile lesion to DNA photosensitized, via an electron transfer mechanism, by three non-steroidal anti-inflammatory drugs (NSAIDs), ketoprofen, tiaprofenic acid and naproxen and their photoproducts during drug photolysis, was investigated using 32 P-end labelled synthetic oligonucleotide. These photooxidative damages were correlated with the photophysical and electrochemical properties...
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