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Objective
IRX3 expression has been functionally associated in obesity‐associated long‐distance susceptibility loci, but the effect of the IRX3 genetic variants on human obesity and obesity‐related metabolism remains uncertain.
Methods
To determine the genetic role of IRX3, we conducted a molecular epidemiological analysis using three haplotype tagging single nucleotide polymorphisms (SNPs; rs8053360,...
Currently, little information is available for major histocompatibility complex (MHC)‐I that conditions the T‐cell response of marmosets. In this study, 471 clones of MHC‐I cDNA sequences were isolated from 12 marmosets. Twenty full‐length sequences of class I G (Caja‐G) alleles were obtained from these marmosets, 15 of them were novel. Among these 20 Caja‐G alleles, 10 were found in individual animals...
Background The Fas/Fas ligand system plays a key role in regulating cell growth and apoptosis. Previous findings have suggested that FAS and FASLG polymorphisms are associated with systemic lupus erythematosus, autoimmune hepatitis, vitiligo and other autoimmune‐related disorders. However, to the best of our knowledge, there is no reported study on the associations between FAS and FASLG polymorphisms...
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