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It has been established that a total of 250 μg of monoclonal anti‐mouse CD3 F(ab′)2 fragments, administered daily (50 μg per dose), induces remission of diabetes in the non‐obese diabetic (NOD) mouse model of autoimmune diabetes by preventing β cells from undergoing further autoimmune attack. We evaluated lower‐dose regimens of monoclonal anti‐CD3 F(ab′)2 in diabetic NOD mice for their efficacy and...
Since the late 1800s surgeons have been treating chronic sinus disease with surgical drainage procedures. For over a century, techniques have been refined based on current theory of sinus function, an understanding of anatomy, and the availability of new technology. We currently benefit from Messerklinger's work on functional endoscopic sinus surgery and the advent of modern endoscopes, as well as...
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