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Background
Extracorporeal photopheresis (ECP) is one of the most widely used and effective cell‐based therapies for the treatment of T‐cell–mediated diseases. The patients' white blood cells (WBCs) are collected by apheresis and exposed to the photosensitizer 8‐methoxypsoralen (8‐MOP) and ultraviolet A (UVA) light before retransfusion. The UVA/8‐MOP combination has been in use in ECP for more than...
BACKGROUND
Traditionally, white blood cells (WBCs) are collected from buffy coats or freshly drawn blood. However, the increasing demand for peripheral blood mononuclear cells (PBMCs) in the research phases of immunological therapy development makes it necessary to identify alternative sources of these cells.
STUDY DESIGN AND METHODS
Leukapheresis products are cost intensive and not offered by...
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