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Key points
We used presynaptic capacitance measurements at the hippocampal mossy fibre terminal at room temperature to measure Ca‐dependence of exo‐ and endocytotic kinetics.
The readily releasable pool (RRP) of synaptic vesicles was released with a time constant of 30–40 ms and was sensitive to Ca buffers, BAPTA and EGTA.
Our data suggest that recruitment of the vesicles to the RRP was Ca‐insensitive...
Purkinje cells (PCs) convey the sole output of the cerebellar cortex to the deep cerebellar nuclei (DCN). DCN neurons are enwrapped in densely organized extracellular matrix structures, known as perineuronal nets (PNNs). PNNs are typically found around fast‐spiking GABAergic interneurons expressing parvalbumin but interestingly also exist surrounding other neurons, such as the neurons in the DCN...
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