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Nanorheology
In article number 2304884, Ricardo Garcia and co‐workers show that nanorheology reveals that cells soften and fluidize upon increasing the frequency of a mechanical stimulus. The response to a time‐dependent deformation might be interpreted as a competition between the cell surface and cytosol. At low frequencies, the viscoelastic response is dominated by interactions at the cell surface...
The nanomechanical response of a cell depends on the frequency at which the cell is probed. The components of the cell that contribute to this property and their interplay are not well understood. Here, two force microscopy methods are integrated to characterize the frequency and/or the velocity‐dependent properties of living cells. It is shown on HeLa and fibroblasts, that cells soften and fluidize...
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