The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Reversed Mitochondrial Dysfunction
Fullerenol nanoparticles are both stable and effective in protecting the degenerating retina. In article number 2205998, Yu Gong, Zhanjun Gu, Haiwei Xu, and co‐workers propose the potential utility of fullerenols for safeguarding the mitochondrial genome to maintain electron transport chain function and simultaneously reversing the abnormal nuclear DNA expression...
Poor therapeutic outcomes of antioxidants in ophthalmologic clinical applications, including glutathione during photoreceptor degeneration in retinitis pigmentosa (RP), are caused by limited anti‐oxidative capacity. In this study, fullerenols are synthesized and proven to be highly efficient in vitro radical scavengers. Fullerenol‐based intravitreal injections significantly improve the flash electroretinogram...
A key characteristic of radiation‐induced oral mucositis (RIOM) is oxidative stress mediated by the “reactive oxygen species (ROS) storm” generated from water radiolysis, resulting in severe pathological lesions, accompanied by a disturbance of oral microbiota. Therefore, a sprayable in situ hydrogel loaded with “free radical sponge” fullerenols (FOH) is developed as antioxidant agent for RIOM radioprotection...
Radiation dermatitis is a common but torturous side effect during radiotherapy, which greatly decreases the life quality of patients and potentially results in detrimental cessation of tumor treatment. Fullerenol, known as “free radical sponge,” is a great choice for skin radioprotection because of its broad‐spectrum free radical scavenging performance, good chemical stability, and biosafety. In this...
The exploration of an old drug for new biomedical applications has an absolute predominance in shortening the clinical conversion time of drugs for clinical application. In this work, carbon nanoparticles suspension injection (CNSI), the first clinically approved carbon nanoparticles in China, is explored as a new nano‐radioprotective agent for potent intestinal radioprotection. CNSI shows powerful...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.