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Generalized aggressive periodontitis (GAgP) is an inflammatory condition resulting in destruction of tooth‐supporting tissues. We examined the production of IL‐1β, IL‐6, tumour necrosis factor (TNF)‐α, IL‐12 and IL‐10 in cultures of peripheral mononuclear cells (MNC) from 10 patients with GAgP and 10 controls stimulated with periodontal pathogens or a control antigen, tetanus toxoid (TT) in the presence...