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Accumulations of fine sediments along continental shelf and deep‐sea bathymetric contours, known as contourite drifts, form a sedimentary record that is dependent on oceanographic processes such as ocean–basin‐scale circulation. A tool used to aid in interpretation of such deposits is the sortable silt hypothesis, which suggests that the mean size of the sortable silt (silt from 10 to 63 μm) within...
Human liver glycogen phosphorylase (HLGP) catalyzes the breakdown of glycogen to maintain serum glucose levels and is a therapeutic target for diabetes. HLGP is regulated by multiple interacting allosteric sites, each of which is a potential drug binding site. We used surface plasmon resonance (SPR) to screen for compounds that bind to the purine allosteric inhibitor site. We determined the affinities...
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