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Objective
Adolescent e‐cigarette use has risen to epidemic levels in the US, revealing a new phenomenon of e‐cigarette vaping‐associated lung injury (EVALI). It is important to better characterize EVALI in critically ill adolescents as this is a vulnerable and rapidly growing demographic.
Methods
This was a retrospective case series of patients ≤21 years old with confirmed or probable EVALI (as...
Nicotinic acetylcholine receptors (nAchRs) are not only key receptors in the autonomic nervous system, but also are present on immune cells. The alpha seven subunit of nAchR (α7nAchR) suppresses pro-inflammation in peripheral monocytes by decreasing pro-inflammatory cytokine production. In spinal cord, α7nAchRs are found on microglia, which are known to induce and maintain pain. We predicted that...
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