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The mechanisms of cell–cell communications are now under intense study by proteomic approaches. Proteomics has unraveled changes in protein profiling as the result of cell interactions mediated by ligand/receptor, hormones, soluble factors, and the content of extracellular vesicles. Besides being a brief overview of the main and profitable methodologies now available (evaluating theory behind the...
DOI: 10.1002/pmic.201500341
Understanding the cell to cell interactions by proteomic approaches. Venn diagram shows the proteomic methodologies that can be applied to analyze proteins differentially expressed in cell to cell interaction mechanisms. The background figures describe data from previous studies published in Proteomics. For details, see the review by Rafael S. Lindoso et al. on page 328...
Acute kidney injury (AKI) is one of the more frequent and lethal pathological conditions seen in intensive care units. Currently available treatments are not totally effective but stem cell‐based therapies are emerging as promising alternatives, especially the use of mesenchymal stromal cells (MSC), although the signaling pathways involved in their beneficial actions are not fully understood. The...
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