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ObjectivesClinical performance of a low coverage, low cost, massively parallel sequencing (MPS)‐based assay to stratify risk of trisomy 21, 18, and 13 pregnancies was determined.
MethodsThe study included 1100 samples with birth outcome or karyotype results, comprising low‐risk patients (84.2%) negative for risk indications from maternal age, serum screening, ultrasound, or family history, and high‐risk...