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The highly conserved angiosperm immune receptor HOPZ‐ACTIVATED RESISTANCE1 (ZAR1) recognises the activity of diverse pathogen effector proteins by monitoring the ZED1‐related kinase (ZRK) family. Understanding how ZAR1 achieves interaction specificity for ZRKs may allow for the expansion of the ZAR1‐kinase recognition repertoire to achieve novel pathogen recognition outside of model species. We took...
Pathogen pressure on hosts can lead to the evolution of genes regulating the innate immune response. By characterizing naturally occurring polymorphisms in immune receptors, we can better understand the molecular determinants of pathogen recognition. ZAR1 is an ancient Arabidopsis thaliana NLR (Nucleotide‐binding [NB] Leucine‐rich‐repeat [LRR] Receptor) that recognizes multiple secreted effector proteins...
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