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Objective
This study investigated the contribution of osteopontin/secreted phosphoprotein 1 (SPP1) to T‐cell regulation in initiation of obesity‐driven adipose tissue (AT) inflammation and macrophage infiltration and the subsequent impact on insulin resistance (IR) and metabolic‐associated fatty liver disease (MAFLD) development.
Methods
SPP1 and T‐cell marker expression was evaluated in AT and...
To investigate whether the endothelial pool of plasminogen activator inhibitor type 1 (PAI-1) plays a role in the development of radiation-induced lung damage, as previously demonstrated in the intestine.Human lung microvascular endothelial cells were exposed to 10 Gy irradiation so as to study their ability to acquire an “activated” phenotype. Mice in which the Cre-Lox strategy was used to produce...
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