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Scope
Data on resveratrol‐(trans‐3,5,4′‐trihydroxystilbene)‐induced caloric‐restriction‐(CR)‐mimicking effects in mice receiving a high‐fat diet (HFD) are contradictory. It is hypothesized that this can possibly stem from different bioactivities of resveratrol (RSV) microbial metabolites.
Methods and results
C57BL/6Rj mice are fed an ad‐libitum HFD supplemented with RSV or its metabolites, dihydroresveratrol...