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To explore the associations of SNPs within hsa‐miR‐605 (rs2043556) and hsa‐miR‐149 (rs2292832) and lifestyle‐related factors with gastrointestinal cancer, a case–control study including 762 cases and 757 controls was conducted. Marginally significant associations were found both for hsa‐miR‐149 rs2292832 with gastric cancer risk (TC + CC vs. TT, OR = 0.68, 95% CI: 0.44–1.04) and for hsa‐miR‐605 rs2043556...