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Background and ObjectivePhotodynamic therapy with 5‐aminolevulinic acid (ALA‐PDT) offers promising results for the treatment of condyloma acuminatum. However, patients have to dwell with pain to benefit from this otherwise effective and safe “off‐label” treatment modality. Several techniques have been explored to control ALA‐PDT‐induced pain, but the desperate search for a universally accepted method...
The hypoxia‐inducible factor‐1 (HIF‐1α) pathway is associated with tumor growth, angiogenesis and metastasis in various carcinomas. Little is known regarding the role of the HIF‐1α signaling pathway in cutaneous squamous cell carcinoma (SCC). We investigated the expression of HIF‐1α, vascular endothelial growth factor (VEGF) and the HIF negative regulator, prolyl hydroxylase domain protein 2 (PHD2),...
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