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During embryonic development of the visual system, retinal ganglion cells (RGCs) project their axons towards the brain, passing through the optic chiasm. Axons are guided on this journey by molecular cues in the environment. The heparan sulphate sulphotransferase (Hst) enzymes Hs2st and Hs6st1 are each known to be required for specific aspects of axon guidance in the developing visual system, as revealed...
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