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Brain aging is a naturally occurring process resulting in the decline of cognitive functions and increased vulnerability to develop age‐associated disorders. Fluctuation in lipid species is crucial for normal brain development and function. However, impaired lipid metabolism and changes in lipid composition in the brain have been increasingly recognized to play a crucial role in physiological aging,...
Background
Autonomic dysfunction is a well‐known dominant symptom in the advanced stages of Parkinson's disease. However, the role of cardiac sympathetic nerves still needs to be elucidated.
Objectives
To evaluate cardiac sympathetic response in Parkinsonian and dyskinetic monkeys.
Methods
Adult male monkeys were divided into 1 of the following 3 groups: controls, 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine–treated...
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