Search results for: Tetsuya Tsujikawa

Items from 1 to 20 out of 30 results

article

Comparison between supervised and physics‐informed unsupervised deep neural networks for estimating cerebral perfusion using multi‐delay arterial spin labeling MRI

Shota Ishida, Yasuhiro Fujiwara, Naoyuki Takei, Hirohiko Kimura, more

NMR in Biomedicine > 37 > 10 > n/a - n/a

This study aimed to implement a physics‐informed unsupervised deep neural network (DNN) to estimate cerebral blood flow (CBF) and arterial transit time (ATT) from multi‐delay arterial spin labeling (ASL), and compare its performance with that of a supervised DNN and the conventional method. Supervised and unsupervised DNNs were trained using simulation data. The accuracy and noise immunity of the...

article

Enhanced parameter estimation in multiparametric arterial spin labeling using artificial neural networks

Shota Ishida, Yasuhiro Fujiwara, Yuki Matta, Naoyuki Takei, more

Magnetic Resonance in Medicine > 92 > 5 > 2163 - 2180

Purpose Multiparametric arterial spin labeling (MP‐ASL) can quantify cerebral blood flow (CBF) and arterial cerebral blood volume (CBV_a). However, its accuracy is compromised owing to its intrinsically low SNR, necessitating complex and time‐consuming parameter estimation. Deep neural networks (DNNs) offer a solution to these limitations. Therefore, we aimed to develop simulation‐based DNNs for MP‐ASL...

article

Estimation of Cerebral Blood Flow and Arterial Transit Time From Multi‐Delay Arterial Spin Labeling MRI Using a Simulation‐Based Supervised Deep Neural Network

Shota Ishida, Makoto Isozaki, Yasuhiro Fujiwara, Naoyuki Takei, more

Journal of Magnetic Resonance Imaging > 57 > 5 > 1477 - 1489

Background An inherently poor signal‐to‐noise ratio (SNR) causes inaccuracy and less precision in cerebral blood flow (CBF) and arterial transit time (ATT) when using arterial spin labeling (ASL). Deep neural network (DNN)‐based parameter estimation can solve these problems. Purpose To reduce the effects of Rician noise on ASL parameter estimation and compute unbiased CBF and ATT using simulation‐based...

article

An eltrombopag‐induced remission of bone‐marrow aplasia accompanied by marked leukoerythroblastosis and splenomegaly

Kotaro Arita, Jun Murakami, Noriko Iwaki, Naoko Hosono, more

British Journal of Haematology > 198 > 5 > e75 - e77

article

Metastatic invasive lobular breast cancer presenting as linitis plastica of the colon: Tumour characterization using [¹⁸F]FES PET/MRI

Tetsuya Tsujikawa, Mizuho Takahashi, Hiroyuki Maeda, Tetsuya Mori, more

Journal of Medical Imaging and Radiation Oncology > 66 > 5 > 634 - 636

Metastatic invasive lobular breast cancer (ILC) to the colon is rare and usually ER‐positive. We present an ER‐negative case of metastatic ILC presenting as linitis plastica of the colon where [¹⁸F]FES PET/MRI allowed the evaluation of the ER phenotypic transformation in the colonic metastasis from the ER‐positive breast ILC in vivo.

article

Radiological perspective of COVID‐19 pneumonia: The early features and progressive behaviour on high‐resolution CT

Tetsuya Tsujikawa, Yukihiro Umeda, Harumi Itoh, Toyohiko Sakai, more

Journal of Medical Imaging and Radiation Oncology > 65 > 2 > 208 - 212

Since the outbreak of Coronavirus disease 2019 (COVID‐19) in China, many researchers have reported the chest CT manifestations of COVID‐19 pneumonia. High‐resolution CT (HRCT) of the lung can provide important clues to understand the progressive behaviour of COVID‐19 pneumonia. This pictorial essay discusses the early features and potential progressive behaviour of COVID‐19 on HRCT of the lung.

article

The vertebral 3′-deoxy-3′-¹⁸F-fluorothymidine uptake predicts the hematological toxicity after systemic chemotherapy in patients with lung cancer

Yukihiro Umeda, Tetsuya Tsujikawa, Masaki Anzai, Miwa Morikawa, more

European Radiology > 2019 > 29 > 7 > 3908-3917

Objectives Although hematological toxicities (HT) are the leading adverse events of systemic chemotherapy, the estimation of severe HT is challenging. Recently, 3′-deoxy-3′-[¹⁸F]-fluorothymidine (¹⁸F-FLT) accumulation with PET has been considered a biomarker of the cell proliferation. This study aims to elucidate whether the vertebral accumulation of ¹⁸F-FLT could estimate severe HT during platinum-doublet...

article

No significant difference found in PET/MRI CBF values reconstructed with CT-atlas-based and ZTE MR attenuation correction

Hidehiko Okazawa, Tetsuya Tsujikawa, Yoshifumi Higashino, Ken-Ichiro Kikuta, more

EJNMMI Research > 2019 > 9 > 1 > 1-9

Background Accurate attenuation correction (AC) is one of the most important issues to be addressed in quantitative brain PET/MRI imaging. Atlas-based MRI AC (AB-MRAC), one of the representative MRAC methods, has been used to estimate the skull attenuation in brain scans. The zero echo time (ZTE) pulse sequence is also expected to provide a better MRAC estimation in brain PET scans. The difference...

article

¹⁸F-FLT PET/MRI for bone marrow failure syndrome-initial experience

Tetsuya Tsujikawa, Toshiki Tasaki, Naoko Hosono, Tetsuya Mori, more

EJNMMI Research > 2019 > 9 > 1 > 1-9

Background Bone marrow failure syndrome (BMFS) is a heterogeneous group of disorders associated with single- or multiple-lineage cytopenia and failure of normal hematopoiesis. We assessed the feasibility of integrated PET/MRI with 3′-deoxy-3′-¹⁸F-fluorothymidine (¹⁸F-FLT) to assess the pathophysiology of whole-body bone marrow for the diagnosis and monitoring of BMFS. Twenty-five consecutive patients...

article

Count-based method for specific binding ratio calculation in [I-123]FP-CIT SPECT analysis

Mahmudur G. M. Rahman, Muhammad M. Islam, Tetsuya Tsujikawa, Yasushi Kiyono, more

Annals of Nuclear Medicine > 2019 > 33 > 1 > 14-21

Objective To calculate the specific binding ratio (SBR) appropriately in dopamine transporter (DAT) imaging, a method for extracting the striatal volume of interest (VOI) was developed. Methods This study included 200 patients (72 ± 10 years) who were suspected of parkinsonian syndromes (PS) or dementia with Lewy body (DLB). The patients were divided into three groups of PS with dopaminergic degeneration,...

article

European research trends in nuclear medicine

Masayuki Inubushi, Mitsuaki Tatsumi, Yuka Yamamoto, Katsuhiko Kato, more

Annals of Nuclear Medicine > 2018 > 32 > 9 > 579-582

Written by associate editors of the Annals of Nuclear Medicine, this invited review article is intended to offer our readers a condensed global view on the high-quality research work that has been published in Europe last year. We have divided this article into five sections. The first three sections from the oncology category include “[¹⁸F]fluorodeoxyglucose (FDG) positron-emission tomography (PET)...

article

Noninvasive method for measurement of cerebral blood flow using O-15 water PET/MRI with ASL correlation

Hidehiko Okazawa, Yoshifumi Higashino, Tetsuya Tsujikawa, Hidetaka Arishima, more

European Journal of Radiology > 2018 > 105 > C > 102-109

A noninvasive image derived input function (IDIF) method was applied to estimate arterial input function from brain H₂¹⁵O-PET/MRI images for the measurement of cerebral blood flow (CBF) because of difficulty in arterial blood sampling during PET/MRI scans. To evaluate accuracy and reproducibility of radioactivity in the internal carotid arteries (ICA) for the IDIF method, a new phantom using a skull...

article

Role of PET/MRI in oral cavity and oropharyngeal cancers based on the 8th edition of the AJCC cancer staging system: a pictorial essay

Tetsuya Tsujikawa, Norihiko Narita, Masafumi Kanno, Tetsuji Takabayashi, more

Annals of Nuclear Medicine > 2018 > 32 > 4 > 239-249

The American Joint Committee on Cancer (AJCC) released the 8th edition of the AJCC cancer staging manual in 2017 that includes significant modifications from the 7th edition in the sections on oral cavity cancer (OCC) and oropharyngeal cancer (OPC). These highlights comprise the incorporation of the depth of invasion and exclusion of extrinsic tongue muscle involvement in the T staging of OCC, the...

article

Assessment of intratumor heterogeneity in mesenchymal uterine tumor by an ¹⁸F-FDG PET/CT texture analysis

Tetsuya Tsujikawa, Makoto Yamamoto, Kunihiro Shono, Shizuka Yamada, more

Annals of Nuclear Medicine > 2017 > 31 > 10 > 752-757

Objective The aim of this study was to retrospectively evaluate the clinical significance of ¹⁸F-FDG PET/CT textural features for discriminating uterine sarcoma from leiomyoma. Methods Fifty-five patients with suspected uterine sarcoma based on ultrasound and MRI findings who underwent pretreatment ¹⁸F-FDG PET/CT were included. Fifteen patients were histopathologically proven to have uterine sarcoma,...

article

¹⁸F-FDG PET radiomics approaches: comparing and clustering features in cervical cancer

Tetsuya Tsujikawa, Tasmiah Rahman, Makoto Yamamoto, Shizuka Yamada, more

Annals of Nuclear Medicine > 2017 > 31 > 9 > 678-685

Objectives The aims of our study were to find the textural features on ¹⁸F-FDG PET/CT which reflect the different histological architectures between cervical cancer subtypes and to make a visual assessment of the association between ¹⁸F-FDG PET textural features in cervical cancer. Methods Eighty-three cervical cancer patients [62 squamous cell carcinomas (SCCs) and 21 non-SCCs (NSCCs)] who had...

article

Pixel-by-pixel precise delay correction for measurement of cerebral hemodynamic parameters in H₂¹⁵O PET study

Muhammad M. Islam, Tetsuya Tsujikawa, Tetsuya Mori, Yasushi Kiyono, more

Annals of Nuclear Medicine > 2017 > 31 > 4 > 283-294

Objective A new method of delay time estimation was proposed to measure precise cerebral blood flow (CBF) and arterial-to-capillary blood volume (V₀) using ¹⁵O-water PET. Methods Nineteen patients with unilateral arterial stenoocclusive lesions were studied to evaluate hemodynamic status before treatment. The delay time of each pixel was calculated using least squares fitting with an arterial blood...

article

Present and future roles of FDG-PET/CT imaging in the management of lung cancer

Kazuhiro Kitajima, Hiroshi Doi, Tomonori Kanda, Tomohiko Yamane, more

Japanese Journal of Radiology > 2016 > 34 > 6 > 387-399

Integrated positron emission tomography/computed tomography (PET/CT) using 2-[¹⁸F]fluoro-2-deoxy-d-glucose (¹⁸F-FDG) has emerged as a powerful tool for combined metabolic and anatomic evaluation in clinical oncologic imaging. This review discusses the utility of ¹⁸F-FDG PET/CT as a tool for managing patients with lung cancer. We discuss different patient management stages, including diagnosis, initial...

article

Evaluation in monkey of two candidate PET radioligands, [¹¹C]RX‐1 and [¹⁸F]RX‐2, for imaging brain 5‐HT₄ receptors

Talakad G. Lohith, Rong Xu, Tetsuya Tsujikawa, Cheryl L. Morse, more

Synapse > 68 > 12 > 613 - 623

The serotonin subtype‐4 (5‐HT₄) receptor, which is known to be involved physiologically in learning and memory, and pathologically in Alzheimer's disease, anxiety, and other neuropsychiatric disorders—has few radioligands readily available for imaging in vivo. We have previously reported two novel 5‐HT₄ receptor radioligands, namely [methoxy‐¹¹C](1‐butylpiperidin‐4‐yl)methyl 4‐amino‐3‐methoxybenzoate;...

article

In vitro and in vivo evaluation of 11C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB1 receptors

Tetsuya Tsujikawa, Sami S. Zoghbi, Jinsoo Hong, Sean R. Donohue, more

NeuroImage > 2014 > 84 > Complete > 733-741

We recently developed a novel cannabinoid subtype-1 (CB ₁ ) receptor radioligand ¹¹ C-SD5024 for brain imaging. This study aimed to evaluate ¹¹ C-SD5024 both in vitro and in vivo and compare it with the other CB ₁ receptor ligands previously used in humans, i.e., ¹¹ C-MePPEP, ¹¹ C-OMAR, ¹⁸ F-MK-9470, and ¹⁸ F-FMPEP-d ₂ . In vitro...

article

Detection of preclinically latent hyperperfusion due to stroke-like episodes by arterial spin-labeling perfusion MRI in MELAS patients

Masamichi Ikawa, Makoto Yoneda, Tomoko Muramatsu, Akiko Matsunaga, more

Mitochondrion > 2013 > 13 > 6 > 676-680

In stroke-like episodes (SEs) of patients with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS), the detection of preclinically latent lesions is a challenge. We report regional cerebral hyperperfusion observed on arterial spin labeling (ASL) perfusion magnetic resonance imaging (MRI) in the preclinical phase more than 3 months before the clinical onset of SEs...

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Search results for: Tetsuya Tsujikawa

Comparison between supervised and physics‐informed unsupervised deep neural networks for estimating cerebral perfusion using multi‐delay arterial spin labeling MRI

Enhanced parameter estimation in multiparametric arterial spin labeling using artificial neural networks

Estimation of Cerebral Blood Flow and Arterial Transit Time From Multi‐Delay Arterial Spin Labeling MRI Using a Simulation‐Based Supervised Deep Neural Network

An eltrombopag‐induced remission of bone‐marrow aplasia accompanied by marked leukoerythroblastosis and splenomegaly

Metastatic invasive lobular breast cancer presenting as linitis plastica of the colon: Tumour characterization using [¹⁸F]FES PET/MRI

Radiological perspective of COVID‐19 pneumonia: The early features and progressive behaviour on high‐resolution CT

The vertebral 3′-deoxy-3′-¹⁸F-fluorothymidine uptake predicts the hematological toxicity after systemic chemotherapy in patients with lung cancer

No significant difference found in PET/MRI CBF values reconstructed with CT-atlas-based and ZTE MR attenuation correction

¹⁸F-FLT PET/MRI for bone marrow failure syndrome-initial experience

Count-based method for specific binding ratio calculation in [I-123]FP-CIT SPECT analysis

European research trends in nuclear medicine

Noninvasive method for measurement of cerebral blood flow using O-15 water PET/MRI with ASL correlation

Role of PET/MRI in oral cavity and oropharyngeal cancers based on the 8th edition of the AJCC cancer staging system: a pictorial essay

Assessment of intratumor heterogeneity in mesenchymal uterine tumor by an ¹⁸F-FDG PET/CT texture analysis

¹⁸F-FDG PET radiomics approaches: comparing and clustering features in cervical cancer

Pixel-by-pixel precise delay correction for measurement of cerebral hemodynamic parameters in H₂¹⁵O PET study

Present and future roles of FDG-PET/CT imaging in the management of lung cancer

Evaluation in monkey of two candidate PET radioligands, [¹¹C]RX‐1 and [¹⁸F]RX‐2, for imaging brain 5‐HT₄ receptors

In vitro and in vivo evaluation of 11C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB1 receptors

Detection of preclinically latent hyperperfusion due to stroke-like episodes by arterial spin-labeling perfusion MRI in MELAS patients

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