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Background
Therapeutic plasma exchange (TPE) removes both pathologic and protective immunoglobulins (Ig). SARS‐CoV‐2 immunity is partially mediated by anti‐SARS‐CoV‐2 spike antibodies (SAb), which impair viral host‐cell invasion. Nonetheless, the systematic effect of TPE on SAb concentration and SARS‐CoV‐2 immunity is unknown.
Methods
Paired plasma waste specimens from the first (first‐TPE) and...
BACKGROUND
The MNS blood group system is defined by three homologous genes: GYPA, GYPB, and GYPE. GYPB encodes for glycophorin B (GPB) carrying S/s and the “universal” antigen U. RBCs of approximately 1% of individuals of African ancestry are U− due to absence of GPB. The U− phenotype has long been attributed to a deletion encompassing GYPB exons 2 to 5 and GYPE exon 1 (GYPB*01N).
STUDY DESIGN...
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