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Introduction
Paroxysmal nocturnal hemoglobinuria (PNH) is caused by a somatic mutation in the PIG‐A gene, which encodes for glycosylphosphatidylinositol, a phospholipid membrane that anchors proteins like CD55 and CD59. These proteins are inhibitors of the complement‐mediated lysis. PNH is diagnosed by flow cytometry, and treatment with eculizumab improves the life quality of patients with severe...