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Hippocampal sharp‐wave ripples (SWRs) support the reactivation of memory representations, relaying information to neocortex during “offline” and sleep‐dependent memory consolidation. While blockade of NMDA receptors (NMDAR) is known to affect both learning and subsequent consolidation, the specific contributions of NMDAR activation to SWR‐associated activity remain unclear. Here, we combine biophysical...
The discovery of cis‐regulatory elements is a challenging problem in bioinformatics, owing to distal locations and context‐specific roles of these elements in controlling gene regulation. Here we review the current bioinformatics methodologies and resources available for systematic discovery of cis‐acting regulatory elements and conserved transcription factor binding sites in the chick genome. In...
A large proportion of Alaska Bureau of Alcohol and Drug Enforcement's time is spent controlling the production and distribution of marijuana. Marijuana in Alaska can originate from within (e.g., Fairbanks and the Matanuska-Susitna Valley) or from outside Alaska (e.g., Latin America, Canada and other locations in the United States of America). However it is difficult to track the supply proportions...
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