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Hepatitis B virus (HBV) infection is one of the major causes of chronic liver inflammation. Tim‐3 acts as a negative regulatory molecule and plays a critical role in immune tolerance. In the current study, we investigated Tim‐3 expression on peripheral monocytes and CD3+CD16/CD56+ natural killer like T (NKT‐like) cells in chronic hepatitis B (CHB) patients. Peripheral blood mononuclear cells (PBMCs)...
The aim of the study was to investigate and compare the clinical manifestations between HLA‐B27+ and HLA‐B27− ankylosing spondylitis (AS) patients in order to obtain knowledge of the impact of HLA‐B27 status on AS, and to inform clinical treatment. A nationwide epidemiological investigation was performed from November 2008 to October 2010. The demographic data and clinical characteristics, and the...
A novel human leukocyte antigen (HLA)‐B allele, B*5535, has been identified in a Chinese individual by sequence‐based typing, which has seven nucleotide changes from the closest matching allele B*5502 resulting in two amino acids changes: 69 Glu→Met; 70 Glu→Ala.
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