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DOI: 10.1002/elps.201900026
The cover picture shows the image of spheroid‐forming glioblastoma cells superimposed on top of a numerical model of the electric field gradient in a cDEP microfluidic device. When an electric field is applied, the spheroid‐forming cells can be enriched by attracting them to the insulating posts in the device.
Cancer stem cells (CSCs) are aggressive subpopulations with increased stem‐like properties. CSCs are usually resistant to most standard therapies and are responsible for tumor repropagation. Similar to normal stem cells, isolation of CSCs is challenging due to the lack of reliable markers. Antigen‐based sorting of CSCs usually requires staining with multiple markers, making the experiments complicated,...
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