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Development of an Fmoc‐based solid‐phase depsipeptide methodology has been hampered by base‐promoted fragmentation and diketoperazine formation upon Fmoc group elimination. Such a strategy would be a useful tool given the number of commercially available Fmoc‐protected residues. Herein we report that the addition of small percentages of organic acids to the Fmoc‐removal cocktail proves effective to...