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UNC93B1 is a trafficking chaperone of endosomal Toll‐like receptors (TLRs) and plays an essential role in the TLR‐mediated innate signaling. However, whether it is also involved in other innate immune sensing or cellular pathways remains largely unexplored. Here we investigated the role of UNC93B1 in cytosolic DNA‐triggered cGAS‐STING signaling in mouse and human cell lines. We showed that while UNC93B1...
Facial landmark detection, as a typical and crucial task in computer vision, is widely used in face recognition, face animation, facial expression analysis, etc. In the past decades, many efforts are devoted to designing robust facial landmark detection algorithms. However, it remains a challenging task due to extreme poses, exaggerated facial expression, unconstrained illumination, etc. In this work,...
Facial landmark detection plays an important role in computer vision. It is a challenging problem due to various poses, exaggerated expressions and partial occlusions. In this work, we propose a Fully End-to-End Cascaded Convolutional Neural Network (FEC-CNN) for more promising facial landmark detection. Specifically, FEC-CNN includes several sub- CNNs, which progressively refine the shape prediction...
Multi-view face detection in open environment is a challenging task due to diverse variations of face appearances and shapes. Most multi-view face detectors depend on multiple models and organize them in parallel, pyramid or tree structure, which compromise between the accuracy and time-cost. Aiming at a more favorable multi-view face detector, we propose a novel funnel-structured cascade (FuSt) detection...
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