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Leukocyte immunoglobulin‐like receptor subfamily B member 1 (LILRB1) has been reported to interact with a wide spectrum of HLA class I (HLA‐I) molecules, albeit with different affinities determined by allelic polymorphisms and conformational features. HLA‐G dimerization and the presence of intracellular Cys residues in HLA‐B7 have been shown to be critical for their recognition by LILRB1. We hypothesized...
Objective One of the side effects of interferon‐alpha (IFN‐α) therapy is interferon‐induced thyroiditis (IIT). The role of lymphocyte subpopulations in IIT remains to be defined. The aim of this study was to assess different peripheral blood lymphocyte subpopulations, mainly CD4+CD25+CD127low/‐FoxP3+ regulatory T cells (Tregs), in patients with chronic hepatitis C virus (HCV) infection who developed...
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