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Eur J Clin Invest 2012
AbstractBackground This study tested the hypothesis that surgical stress and the host response to this trauma trigger an inflammatory cascade in which the neutrophil plays a central role. We hypothesised that pre‐operative neutrophil migratory responses will correlate with post‐operative clinical outcome in our shock model of open‐heart surgery patients. We also tested the...
Neutrophils, cells of the innate immune system, contain an array of proteases and reactive oxygen species‐generating enzymes that assist in controlling the invasion of bacteria and pathogens. The high content of intracellular proteolytic enzymes makes them difficult cells to work with as they can degrade proteins of potential interest. Here, we describe the benefits of heat treatment of neutrophils...
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