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Yes‐associated protein (YAP), a key effector of the Hippo signaling pathway, is expressed in the nucleus of spermatogonia in mice, suggesting a potential role in spermatogenesis. Here, we report the generation of a conditional knockout mouse model (Yapflox/flox; Ddx4cre/+) that specifically inactivates Yap in the germ cells. The inactivation of Yap in spermatogonia was found to be highly efficient...