Search results for: O. Dumortier

Items from 1 to 7 out of 7 results

article

Corrigendum to Biotechnology Progress 2003, 19, 928–935 by Y.O. Shin, M.E. Weber, and J.H. Vera

Grazyna Wilczek‐Vera, Younok O. Dumortier Shin, Eva Rodil, Juan H. Vera

Biotechnology Progress > 34 > 2 > 552 - 552

article

Shaping and preserving β‐cell identity with microRNAs

O. Dumortier, G. Fabris, E. Van Obberghen

Diabetes, Obesity and Metabolism > 18 > S1 > 51 - 57

The highly sophisticated identity of pancreatic β‐cells is geared to accomplish its unique feat of providing insulin for organismal glucose and lipid homeostasis. This requires a particular and streamlined fuel metabolism which defines mature β‐cells as glucose sensors linked to an insulin exocytosis machinery. The establishment of an appropriate β‐cell mass and function during development as well...

article

O74 Programmation foetale du diabète de type 2 : Rôle du miR-375 dans l’insuffisance pancréatique

O. Dumortier, C. Hinault, N. Gautier, E.V. Obberghen

Diabetes and Metabolism > 2013 > 39 > Supplement 1 > A18

Chez l’homme l’environnement intra-utérin est un facteur déterminant pour la santé à long terme de la progéniture. En effet, la malnutrition maternelle augmente le risque de développer un diabète de type 2 (DT2) chez les descendants. Bien que les conséquences d’un environnement prénatal perturbé sur le développement embryonnaire soient connues, les mécanismes responsables ne sont pas élucidés. Chez...

article

MicroRNAs in pancreas development

O. Dumortier, E. Obberghen

Diabetes, Obesity and Metabolism > 14 > s3 > 22 - 28

The development of the pancreas is a tightly regulated process involving extensive morphogenesis, proliferation and differentiation of the epithelium. The finely orchestrated control of gene expression plays a key role in this equilibrium by coordinating the expression of selected gene products at specific moments and in precise locations. MicroRNAs (miRNAs) are small non‐coding RNAs that function...

article

Different mechanisms operating during different critical time-windows reduce rat fetal beta cell mass due to a maternal low-protein or low-energy diet

O. Dumortier, B. Blondeau, B. Duvillié, B. Reusens, more

Diabetologia > 2007 > 50 > 12 > 2495-2503

Aims/hypothesis Adverse events during intra-uterine life may programme organ growth and favour disease later in life. In animals, protein or energy restriction during gestation alters the development of the endocrine pancreas, even though the duration of malnutrition is different. Here, we evaluate the specific effects of both diets during different periods of gestation and the mechanisms underlying...

article

Carbon nanotubes-Fe-Alumina nanocomposites. Part II: microstructure and mechanical properties of the hot-Pressed composites

Ch. Laurent, A. Peigney, O. Dumortier, A. Rousset

Journal of the European Ceramic Society > 1998 > 18 > 14 > 2005-2013

Carbon nanotubes-Fe-Al ₂ O ₃ massive composites have been prepared by hot-pressing the corresponding composite powders, in which the carbon nanotubes are arranged in bundles smaller than 100nm in diameter and several tens of micrometers long, forming a web-like network around the Fe-Al ₂ O ₃ grains. In the powders, the quantity and the quality of the carbon nanotubes...

article

Carbon nanotubes-Fe-alumina nanocomposites. Part I: influence of the Fe content on the synthesis of powders

A. Peigney, Ch. Laurent, O. Dumortier, A. Rousset

Journal of the European Ceramic Society > 1998 > 18 > 14 > 1995-2004

Oxides based on α-alumina and containing various amounts of Fe (2, 5, 10, 15 and 20 cat%) were prepared by decomposition and calcination of the corresponding mixed-oxalates. Selective reduction of the oxides in a H ₂ -CH ₄ atmosphere produces nanometric Fe particles which are active for the in-situ nucleation and growth of carbon nanotubes. These form bundles smaller than 100nm in...

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Search results for: O. Dumortier

Corrigendum to Biotechnology Progress 2003, 19, 928–935 by Y.O. Shin, M.E. Weber, and J.H. Vera

Shaping and preserving β‐cell identity with microRNAs

O74 Programmation foetale du diabète de type 2 : Rôle du miR-375 dans l’insuffisance pancréatique

MicroRNAs in pancreas development

Different mechanisms operating during different critical time-windows reduce rat fetal beta cell mass due to a maternal low-protein or low-energy diet

Carbon nanotubes-Fe-Alumina nanocomposites. Part II: microstructure and mechanical properties of the hot-Pressed composites

Carbon nanotubes-Fe-alumina nanocomposites. Part I: influence of the Fe content on the synthesis of powders

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