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Aim: We investigated how GW800644, the first pharmacologically selective murine peroxisome proliferator‐activated receptor δ (PPARδ) agonist, affects energy balance, glucose homeostasis and fuel utilization by muscle in obese mice.
Methods: Potencies were determined in transactivation assays. Oral glucose tolerance was determined after 14 and 22 days' administration (10 mg/kg body weight, twice daily)...