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This paper presents a glucose-responsive micro device capable of modulating drug diffusion rates according to changes in environmental glucose levels. New glucose-responsive composite membranes with enhanced mechanical strength were developed, in which chemically immobilized glucose oxidase and pH-responsive hydrogel nanoparticles were embedded within PDMS micro grids, functioning as intelligent ‘nano-valves’...
A drug-delivery microdevice integrating pH-responsive nano-hydrogel composite membranes functioning as intelligent nano valves is described. The polymeric microdevices are monolithic without requiring peripheral control hardware or additional components for controlling drug-release rates. pH-responsive nanoparticles were synthesized and embedded into a composite membrane. The resulting pH-responsive...
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