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Anti‐TRK targeted therapies offer opportunities to treat patients with advanced NTRK1/2/3‐rearranged cancers. Beyond NTRK‐rearranged secretory breast carcinomas, little is known about NTRK rearrangements and the expression of TRK proteins in non‐secretory breast carcinomas. We search for TRK proteins expressions using pan‐TRK immunohistochemistry and NTRK1, NTRK2 and NTRK3 rearrangements using fluorescent...
Several therapeutics targets have emerged to treat patients with non–small-cell lung carcinoma (NSCLC), with numerous biomarkers available to test for treatment choices. Minimum tumor wastage is necessary to permit the analysis of every potentially relevant target. Searching for targetable ALK and ROS1 rearrangements is now mandatory in NSCLC. In the present study, we evaluated the performance of...
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