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Objective
To report a novel mutation in GHR and to characterize a novel mechanism of nonclassical growth hormone insensitivity.
Context
Laron syndrome (LS) is a well‐described disorder of growth hormone insensitivity due to mutations in the growth hormone receptor (GHR) that leads to short stature. Biochemically, LS patients classically have elevated levels of growth hormone (GH), but low levels...