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Background
Patch testing is the gold standard for identifying culprit allergens in allergic contact dermatitis; however, it is laborious and positive reactions are difficult to quantitate. Development of complementary in vitro tests is, therefore, of great importance.
Objectives
This study aimed to improve the in vitro lymphocyte proliferation test (LPT) to detect allergic responses to nickel (Ni),...
Atopic dermatitis (AD) is a chronic and relapsing inflammatory skin disease. Molecular characterization of AD shows an underlying inflammation with tissue infiltration of T helper (TH) 2 cells and increased IL‐4 and IL‐13. The multifaceted roles of IL‐4 and IL‐13 in allergic disease development make IL‐4Rα an attractive target for treatment strategies, and a neutralizing monoclonal antibody which...
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