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Objective
The evidence for a prospective association of vitamin D deficiency with the occurrence of late‐life depression is limited. We aimed to study the long‐term association between vitamin D serum levels and depression in a large population‐based study of older adults.
Method
We included 3251 participants from the Rotterdam Study, aged 55 and older with 32 400 person‐years follow‐up for depression...
Rationale Evidence suggests that depression is cross-sectionally and longitudinally associated with activation of inflammatory response system. A few studies, however, have investigated the longitudinal relationship between raised inflammatory biomarkers and persistence of depressive symptoms. We examined the temporal relationship between serum levels of inflammatory biomarkers and persistence of...
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