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Objectives
The objective of this study was to conduct an umbrella review of therapeutic studies relevant to emergency medicine, analyzing patterns in effect size, power, and signals of potential bias across an entire field of clinical research.
Methods
We combined topic‐ and journal‐driven searches of PubMed and Google Scholar for published articles of systematic reviews and meta‐analyses (SRMA)...
Background
Advances in deep sequencing technology have uncovered a widespread, protumorigenic role of guanine nucleotide‐binding (G protein) α (GNA) subunits, particularly GNA subunits Gs (GNAS), Gq (GNAQ), and G11 (GNA11) (GNA*), in a diverse collection of malignancies. The objectives of the current study were: 1) to determine GNA* aberration status in a cohort of 1348 patients with cancer and 2)...
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