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We have reexamined the role of endogenous thrombospondin-1 (TSP1) in growth and motility of vascular smooth muscle cells (SMCs). Based on the ability of aortic-derived SMCs isolated from TSP1 null mice and grown in the absence of exogenous TSP1 to grow at comparable rates and to a slightly higher density than equivalent cells from wild-type mice, TSP1 is not necessary for their growth. Low concentrations...
This article has been retracted by the author as it was a duplication of the article "Surgical Research and the Ethics of Being First" by Isenberg JS which was published in the Journal of the Philosophy of Surgery and Medicine 2002; 1: 45-54. An erratum to this article is available at http://dx.doi.org/10.1007/s10790-013-9398-5 .
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