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Wheezing is common in childhood. However, current prediction models of pediatric asthma have only modest accuracy. Novel biomarkers and definition of subphenotypes may improve asthma prediction. Interleukin‐1‐receptor‐like‐1 (IL1RL1 or ST2) is a well‐replicated asthma gene and associates with eosinophilia. We investigated whether serum sST2 predicts asthma and asthma with elevated exhaled NO (FeNO),...
BackgroundInterleukin‐33 (IL‐33) has been subject of extensive study in the context of inflammatory disorders, particularly in asthma. Many human biological samples, including serum, have been used to determine the protein levels of IL‐33, aiming to investigate its involvement in asthma. Reliable methods are required to study the association of IL‐33 with disease, especially considering the complex...
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