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Background We present a case of gamma-delta T-cell lymphoma that does not fit the current World Health Organization classifications. Case presentation A 74-year-old Caribbean-American woman presented with lymphocytosis, pruritus, and non-drenching night sweats. Bone marrow and peripheral blood analyses both confirmed the diagnosis of gamma-delta T-cell lymphoma. An axillary lymph node biopsy was...
Although BCR-ABL negative myeloproliferative neoplasms (MPN) – and especially myelofibrosis (MF) – are recognized to be associated with autoimmune phenomena, immune derangements in MPN have been much less studied. Myeloid-derived suppressor cells (MDSC) are one type of important immune modulator cell. Therefore, we studied MDSCs in MPN disease. MDSCs were studied in two cohorts: the first cohort was...
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