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Background Maize, a crop of global significance, is vulnerable to a variety of biotic stresses resulting in economic losses. Fusarium verticillioides (teleomorph Gibberella moniliformis) is one of the key fungal pathogens of maize, causing ear rots and stalk rots. To better understand the genetic mechanisms involved in maize defense as well as F. verticillioides virulence, a systematic investigation...
Multi-target therapeutics has been shown to be effective for treating complex diseases. In this paper, we propose a novel stochastic search algorithm that can be effectively used for combinatorial drug optimization. The proposed algorithm aims to enhance existing drug optimization, including the Gur Game algorithm, where the key of the proposed approach lies in utilizing a reference concentration...
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