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Fenofibrate is a synthetic ligand for peroxisome proliferator-activated receptors subtype alpha (PPARα); it is used for the treatment of a wide range of metabolic diseases such as hypertriglyceridemia, dyslipidemia, diabetes and various neurodegenerative diseases. We have studied the effect of fenofibrate on β-oxidation of fatty acids and related free-radical processes. The most effective concentration...