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Introduction Many clinical manifestations can be related to Tropheryma whipplei infection. Case report We report a Tropheryma whipplei limbic encephalitis developed as a relapse of classical Whipple’s disease. Discussion This case is to the best of our knowledge the first proof of the effective brain–blood barrier crossing of both doxycycline and hydroxychloroquine as demonstrated by direct concentration...
Whipple’s disease usually presents as chronic joint pain followed by digestive manifestations. However, many different presentations have been described in the literature. We report here the first proven case of muscular vasculitis related to Whipple’s disease, associated with an expansion of circulating activated γδ T lymphocytes.
Les scedosporioses invasives sont causées principalement par des champignons dont la taxonomie a récemment changé, Lomentospora prolificans (syn. Scedosporium prolificans) et le complexe Scedosporium/Pseudallescheria. Ils sont responsables d’infections variées chez des patients immunodéprimés, plus rarement chez l’immunocompétent. Leur haut niveau de résistance aux antifongiques rend la prise en charge...
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