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Vaccine adjuvants and vaccines may induce autoimmune and inflammatory manifestations in susceptible individuals. To date most human vaccine trials utilize aluminum (Al) adjuvants as placebos despite much evidence showing that Al in vaccine-relevant exposures can be toxic to humans and animals. We sought to evaluate the effects of Al adjuvant and the HPV vaccine Gardasil versus the true placebo on...
Vasculitides are a heterogeneous group of autoimmune‐mediated inflammatory diseases involving blood vessels of different types and sizes. This chapter discusses the main etiopathogenic hypotheses for how vasculitic processes may be triggered by vaccines. It analyzes all the relevant Medline records from 1970 through July 2013 relating to the onset of different types of vasculitides following exposure...
BackgroundThe increasing prevalence of cancer survivors who are infertile due to gonadal failure highlights the importance of fertility preservation prior to gonadotoxic treatments. Adolescent cancer patients may not be mature enough to produce sperm by masturbation, leading to the use of alternative methods for obtaining sperm for cryopreservation. The aim of the current study was to evaluate the...
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