Search results for: María Díez-Cirarda

Items from 1 to 11 out of 11 results

article

A data‐driven approach to complement the A/T/(N) classification system using CSF biomarkers

Laura Hernández‐Lorenzo, Maria José Gil‐Moreno, Isabel Ortega‐Madueño, Maria Cruz Cárdenas, more

CNS Neuroscience & Therapeutics > 30 > 2 > n/a - n/a

Aims The AT(N) classification system not only improved the biological characterization of Alzheimer's disease (AD) but also raised challenges for its clinical application. Unbiased, data‐driven techniques such as clustering may help optimize it, rendering informative categories on biomarkers' values. Methods We compared the diagnostic and prognostic abilities of CSF biomarkers clustering results...

article

Persistent olfactory dysfunction after COVID‐19 is associated with reduced perfusion in the frontal lobe

Miguel Yus, Jordi A. Matias‐Guiu, Lidia Gil‐Martínez, Natividad Gómez‐Ruiz, more

Acta Neurologica Scandinavica > 146 > 2 > 194 - 198

Background Olfactory dysfunction is common during SARS‐CoV‐2 infection. The pathophysiology of the persistence of this symptom and the potential relationship with central nervous system involvement is unknown. Aim of the study To evaluate the neural correlates of persistent olfactory dysfunction in a series of patients with post‐COVID syndrome. Methods Eighty‐two patients with post‐COVID syndrome...

article

Parameters from site classification to harmonize MRI clinical studies: Application to a multi‐site Parkinson's disease dataset

Gemma Monte‐Rubio, Barbara Segura, Antonio Strafella, Thilo Eimeren, more

Human Brain Mapping > 43 > 10 > 3130 - 3142

Multi‐site MRI datasets are crucial for big data research. However, neuroimaging studies must face the batch effect. Here, we propose an approach that uses the predictive probabilities provided by Gaussian processes (GPs) to harmonize clinical‐based studies. A multi‐site dataset of 216 Parkinson's disease (PD) patients and 87 healthy subjects (HS) was used. We performed a site GP classification using...

article

Cover Image

Gemma Monte‐Rubio, Barbara Segura, Antonio Strafella, Thilo Eimeren, more

Human Brain Mapping > 43 > 10 > n/a - n/a

COVER ILLUSTRATION Larger cohorts of multi‐site MRI data are crucial for neuroimaging research. Harmonization strategies become necessary. The WHARMPA method is user‐friendly and provides a powerful solution to clean the analyses by removing variability associated with the differences between sites. These Weighted HARMonization PArameters encode global site effects quantitatively without complex implementations...

article

Extra‐striatal dopamine in Parkinson's disease with rapid eye movement sleep behavior disorder

Mikaeel Valli, Sang Soo Cho, Mario Masellis, Robert Chen, more

Journal of Neuroscience Research > 99 > 4 > 1177 - 1187

Rapid eye movement sleep behavior disorder (RBD) is a common condition found in more than 50% of the patients with Parkinson's disease (PD). Molecular imaging shows that PD with RBD (PD‐RBD+) have lower striatal dopamine transporter activity within the caudate and putamen relative to PD without RBD (PD‐RBD−). However, the characterization of the extra‐striatal dopamine within the mesocortical and...

article

Graph theory analysis of the dopamine D2 receptor network in Parkinson’s disease patients with cognitive decline

Alexander S. Mihaescu, Jinhee Kim, Mario Masellis, Ariel Graff‐Guerrero, more

Journal of Neuroscience Research > 99 > 3 > 947 - 965

Cognitive decline in Parkinson's disease (PD) is a common sequela of the disorder that has a large impact on patient well‐being. Its physiological etiology, however, remains elusive. Our study used graph theory analysis to investigate the large‐scale topological patterns of the extrastriatal dopamine D2 receptor network. We used positron emission tomography with [¹¹C]FLB‐457 to measure the binding...

article

Dynamic functional connectivity in Parkinson's disease patients with mild cognitive impairment and normal cognition

María Díez-Cirarda, Antonio P. Strafella, Jinhee Kim, Javier Peña, more

NeuroImage: Clinical > 2018 > 17 > C > 847-855

The objective was to assess dynamic functional connectivity (FC) and local/global connectivity in Parkinson's disease (PD) patients with mild cognitive impairment (PD-MCI) and with normal cognition (PD-NC).The sample included 35 PD patients and 26 healthy controls (HC). Cognitive assessment followed an extensive neuropsychological battery. For resting-state functional MRI (rs-fMRI) analysis, independent...

article

Altered functional connectivity in the default mode network is associated with cognitive impairment and brain anatomical changes in Parkinson's disease

Olaia Lucas-Jiménez, Natalia Ojeda, Javier Peña, María Díez-Cirarda, more

Parkinsonism & Related Disorders > 2016 > 33 > C > 58-64

To assess whether functional neural connectivity is disrupted between the regions of the default mode network (DMN) in Parkinson's disease (PD) and how this connectivity is related to cognition, brain gray matter structure and white matter integrity and diffusivity.Thirty-seven PD patients and 16 healthy controls were evaluated, using resting-state functional magnetic resonance imaging (MRI), T1-weighted...

article

Increased brain connectivity and activation after cognitive rehabilitation in Parkinson’s disease: a randomized controlled trial

María Díez-Cirarda, Natalia Ojeda, Javier Peña, Alberto Cabrera-Zubizarreta, more

Brain Imaging and Behavior > 2017 > 11 > 6 > 1640-1651

Cognitive rehabilitation programs have demonstrated efficacy in improving cognitive functions in Parkinson’s disease (PD), but little is known about cerebral changes associated with an integrative cognitive rehabilitation in PD. To assess structural and functional cerebral changes in PD patients, after attending a three-month integrative cognitive rehabilitation program (REHACOP). Forty-four PD patients...

article

Apathy is associated to altered resting-state functional connectivity and structural changes in Parkinson's disease

Olaia Lucas-Jiménez, Natalia Ojeda, Javier Peña, Maria Díez-Cirarda, more

Parkinsonism and Related Disorders > 2016 > 22 > Supplement 2 > e157

article

Short and long term effect of cognitive rehabilitation in mild cognitive impairment subtypes in Parkinson's disease

Maria Diez-Cirarda, Natalia Ojeda, Javier Peña, Olaia Lucas-Jimenez, more

Parkinsonism and Related Disorders > 2016 > 22 > Supplement 2 > e74

Filter options

Publication date

Last year (1)
Last 3 years (4)

Close

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

From:

To:
Set your own date range

Keywords

Data set

Wiley (6)
Elsevier (4)
Springer (1)

INFONA - science communication portal

Search results for: María Díez-Cirarda

Add recipient

Sending message cancelled

Are you sure you want to cancel sending this message?

Send message

Filter options

Publication date

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

Keywords

Data set

Journal

Reporting an error / abuse

Sending the report failed

Accessibility options