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Mit der klinischen Zulassung genetisch modifizierter T‑Zellen, die das CD19-Molekül (CD: „cluster of differentiation“) auf malignen Zellen der akuten lymphoblastischen Leukämie über einen synthetischen, sog. chimären Antigenrezeptor (CAR) erkennen, beginnt auch in Deutschland ein neues Zeitalter der personalisierten zellulären Immuntherapie. Der innovative Wirkmechanismus besteht darin, dass der CAR...
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