Search results for: Michael Krause

Items from 1 to 20 out of 66 results

article

Self‐calibration strategies for reducing systematic slope measurement errors of autocollimators in deflectometric profilometry

Ralf D. Geckeler, Andreas Just, Michael Krause, Olaf Schnabel, more

Journal of Synchrotron Radiation > 31 > 4 > 670 - 680

Deflectometric profilometers are used to precisely measure the form of beam shaping optics of synchrotrons and X‐ray free‐electron lasers. They often utilize autocollimators which measure slope by evaluating the displacement of a reticle image on a detector. Based on our privileged access to the raw image data of an autocollimator, novel strategies to reduce the systematic measurement errors by using...

article

Eleclazine exhibits enhanced selectivity for long QT syndrome type 3–associated late Na+ current

Nesrine El-Bizri, Cheng Xie, Lynda Liu, James Limberis, more

Heart Rhythm > 2018 > 15 > 2 > 277-286

Eleclazine (GS-6615) is a sodium channel blocker designed to improve the selectivity for cardiac late Na⁺ current (I_Na) over peak I_Na.The goals of this study were to investigate the inhibition of late I_Na by eleclazine using a sample of long QT syndrome type 3 (LQT3) and overlap LQT3/Brugada syndrome mutant channels; to compare the apparent binding rates for eleclazine with those for other class 1...

article

A new class of very efficient algorithms for local dimming

Michael Krause, Martin Riplinger, Alfred K. Louis, Chihao Xu

Optimization and Engineering > 2018 > 19 > 1 > 1-17

One of the main aspects of today’s computing, especially on mobile devices, is power consumption. It affects the lifetime of batteries and has ecological aspects. In the near future, a significant proportion of the energy of mobile devices will be spent on displays. Thus, dimming, especially local dimming of displays, increases the comfort of these mobile devices. A convenient side-effect of local...

chapter

Challenges in Modelling and Using Quality of Context (QoC)

Michael Krause, Iris Hochstatter

Lecture Notes in Computer Science > Mobility Aware Technologies and Applications > 324-333

Context-awareness in the vision of Ubiquitous Computing implies more than just the integration of sensor data into applications. It promises vast benefits from automated sharing and combining of knowledge about current situations. We emphasize the necessity of quality of context (QoC) to enable and improve the automatic rating and processing of context information. We derive requirements for handling...

chapter

A Context Middleware Using an Ontology-Based Information Model

Iris Hochstatter, Michael Duergner, Michael Krause

Lecture Notes in Computer Science > Dependable and Adaptable Networks and Services > Technical Session 1: Middleware and Supportive Services > 17-24

For the adaptation of services to the current situation of a user, the services are in need of specific context information. The acquisition of context in highly dynamic environments is a complex process as the appropriate context sources are not known in advance. Moreover, to realize Mark Weiser’s vision of ubiquitous computing, many services on the one hand and a good deal of context information...

chapter

Experimental Evaluations of Touch Interaction Considering Automotive Requirements

Andreas Haslbeck, Severina Popova, Michael Krause, Katrina Pecot, more

Lecture Notes in Computer Science > Human-Computer Interaction. Interaction Techniques and Environments > Touch-Based and Haptic Interaction > 23-32

Three different usability studies present evaluation methods for cross-domain human-computer-interaction. The first study compares different input devices like touch screen, turn-push-controller or handwriting recognition under regard of human error probability, input speed and subjective usability assessment. The other experiments had a focus on typical automotive issues: interruptibility and the...

chapter

Technical Potential of Solar Thermal Driven Open Cycle Absorption Processes for Industrial and Comfort Air Conditioning

Roland Heinzen, Michael Krause, Ulrike Jordan, Klaus Vajen

Proceedings of ISES World Congress 2007 (Vol. I – Vol. V) > Solar Collector Technologies and Systems > 809-813

The open absorption process is basically an air drying process. Applications for this process can be found in the sector of industrial and comfort air conditioning. In this investigation seven categories of applications are described and characterized concerning their specific requests for temperature and humidity. Possible system configurations of an open absorption system are presented for...

chapter

Automatic Fault Detection for Big Solar Heating Systems

Frank Wiese, Klaus Vajen, Michael Krause, Andreas Knoch

Proceedings of ISES World Congress 2007 (Vol. I – Vol. V) > Solar Collector Technologies and Systems > 759-763

Solar heating systems require a permanent function control to ensure a proper operation. A new method with automatic fault detection for large solar heating systems has been developed. In a first and second step faults are identified by checking the reliability of individual measured values and via logical expressions of linked measured values. Since not all faults are identified by these simple procedures,...

article

Fast retinal vessel analysis

Michael Krause, Ralph Maria Alles, Bernhard Burgeth, Joachim Weickert

Journal of Real-Time Image Processing > 2016 > 11 > 2 > 413-422

We introduce a fast image processing system that allows to analyse digital data-bases of retinal images in a short time, and to process the image in situ while the patient is examined. While it achieves a comparable quality as state-of-the-art methods, it differs from most of them by the fact that it is extremely fast. Retinal blood vessels are enhanced via convolution with the second derivative of...

article

A new local dimming algorithm based on the simplex method

Martin Riplinger, Michael Krause, Alfred K. Louis, Chihao Xu

Computational Optimization and Applications > 2016 > 64 > 1 > 243-263

A recently arising important feature of mobile computing is power efficiency. Economical power management allows to increase the battery lifetime of tablets, mobile phones and so on. As the display of those devices yields the largest part of power consumption in the near future, it is necessary to reduce the power consumption of them. This can be achieved by dimming, especially by local dimming, i...

article

Use of System of Systems and Decentralized Optimization Concepts for Integrated Traffic Control via Dynamic Signalization and Embedded Speed Recommendation

Ugnius Aliubavicius, Julia Obermaier, Walid Fourati, Diamantis Manolis, more

Transportation Research Procedia > 2016 > 14 > C > 3416-3425

In the frame of the European research project Local4Global, urban traffic control is one of the demonstrative use cases of a developed decentralized control method based on the Technical System of Systems (TSoS) concept and using machine learning capabilities. TSoS concept consists of dividing the system to semiautonomous elementary systems, called constituent systems, which shall enjoy to a major...

article

New frontiers in angle metrology at the PTB

Ralf D. Geckeler, Michael Krause, Andreas Just, Oliver Kranz, more

Measurement > 2015 > 73 > Complete > 231-238

An overview of the current status of angle metrology at the Physikalisch-Technische Bundesanstalt (PTB), the national metrology institute of Germany, is provided. We present our novel self-calibration method for the fast and precise in-situ calibration of angle encoders without recourse to external reference standards which relies on a suitable geometric arrangement of multiple heads which read out...

article

The pan‐deacetylase inhibitor panobinostat suppresses the expression of oncogenic miRNAs in hepatocellular carcinoma cell lines

Alexander Henrici, Roberta Montalbano, Daniel Neureiter, Michael Krause, more

Molecular Carcinogenesis > 54 > 8 > 585 - 597

Deacetylase inhibitors (DACi) are a new class of drugs with a broad spectrum of mechanisms that favor their application in cancer therapy. Currently, the exact mechanisms and cellular effects of DACi have not been fully elucidated. In addition to their effects on histone acetylation, DACi can interfere with gene expression via miRNA pathways. Treatment with panobinostat (LBH589), a novel potent DACi,...

article

Agricultural trade and tropical deforestation: interactions and related policy options

Christoph Schmitz, Ulrich Kreidenweis, Hermann Lotze-Campen, Alexander Popp, more

Regional Environmental Change > 2015 > 15 > 8 > 1757-1772

The extensive clearing of tropical forests throughout past decades has been partly assigned to increased trade in agricultural goods. Since further trade liberalisation can be expected, remaining rainforests are likely to face additional threats with negative implications for climate mitigation and the local environment. We apply a spatially explicit economic land-use model coupled to a biophysical...

article

Zr coordination change during crystallization of MgO–Al2O3–SiO2–ZrO2 glass ceramics

Christian Patzig, Thomas Höche, Yongfeng Hu, Hidekazu Ikeno, more

Journal of Non-Crystalline Solids > 2014 > 384 > Complete > 47-54

Glasses with the composition 51.9 SiO ₂ • 21.2 MgO • 21.2 Al ₂ O ₃ • 5.7 ZrO ₂ (in mol%) are transformed into high- and low-quartz solid solution glass ceramics, by a heat treatment at 950°C for different periods of time. X-ray absorption near edge structure (XANES) studies at the Zr L _2,3 edge show a transition of the Zr coordination number from approximately...

article

Pituitary adenylate cyclase‐activating polypeptide (PACAP) inhibits the slow afterhyperpolarizing current sI_AHP in CA1 pyramidal neurons by activating multiple signaling pathways

Ruth D.T. Taylor, Marita Grønning Madsen, Michael Krause, Marisol Sampedro‐Castañeda, more

Hippocampus > 24 > 1 > 32 - 43

The slow afterhyperpolarizing current (sI_AHP) is a calcium‐dependent potassium current that underlies the late phase of spike frequency adaptation in hippocampal and neocortical neurons. sI_AHP is a well‐known target of modulation by several neurotransmitters acting via the cyclic AMP (cAMP) and protein kinase A (PKA)‐dependent pathway. The neuropeptide pituitary adenylate cyclase activating peptide...

article

Mixed‐polarization phenotype of ascites‐associated macrophages in human ovarian carcinoma: Correlation of CD163 expression, cytokine levels and early relapse

Silke Reinartz, Tim Schumann, Florian Finkernagel, Annika Wortmann, more

International Journal of Cancer > 134 > 1 > 32 - 42

Ovarian cancer is typically accompanied by the occurrence of malignant ascites containing large number of macrophages. It has been suggested that these tumor‐associated macrophages (TAMs) are skewed to alternative polarization (M2) and thereby play an essential role in therapy resistance and metastatic spread. In our study, we have investigated the nature, regulation and clinical correlations of TAM...

chapter

Cascading Raman lasers for reducing their threshold

Hagen Renner, Michael Krause

2013 IEEE 4th International Conference on Photonics (ICP) > 190 - 192

2013 IEEE 4th International Conference on Photonics (ICP)

We show that the threshold pump power of Raman lasers can be significantly reduced by adding a low-loss intermediate cavity while a high conversion efficiency at large pump powers is maintained.

article

Unconventional reservoir potential of the upper Permian Zechstein Group: a slope to basin sequence stratigraphic and sedimentological evaluation of carbonates and organic-rich mudrocks, Northern Germany

Ursula Hammes, Michael Krause, Maria Mutti

Environmental Earth Sciences > 2013 > 70 > 8 > 3797-3816

The Late Permian Zechstein Group in northeastern Germany is characterized by shelf and slope carbonates that rimmed a basin extending from eastern England through the Netherlands and Germany to Poland. Conventional reservoirs are found in grainstones rimming islands created by pre-existing paleohighs and platform-rimming shoals that compose steep margins in the north and ramp deposits in the southern...

article

Continuous plankton recorder underestimates zooplankton abundance

Joachim W. Dippner, Michael Krause

Journal of Marine Systems > 2013 > 111-112 > Complete > 263-268

A comparison between monthly mean Continuous Plankton Recorder (CPR) data and zooplankton data caught during winter and early spring with different sampling devices in the North Sea is presented to estimate the relative error in abundance of CPR measurements. CPR underestimates the abundance of zooplankton by a factor 25 during winter and early spring and by a factor 18 if Oithona spp. is not considered...

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INFONA - science communication portal

Search results for: Michael Krause

Self‐calibration strategies for reducing systematic slope measurement errors of autocollimators in deflectometric profilometry

Eleclazine exhibits enhanced selectivity for long QT syndrome type 3–associated late Na+ current

A new class of very efficient algorithms for local dimming

Challenges in Modelling and Using Quality of Context (QoC)

A Context Middleware Using an Ontology-Based Information Model

Experimental Evaluations of Touch Interaction Considering Automotive Requirements

Technical Potential of Solar Thermal Driven Open Cycle Absorption Processes for Industrial and Comfort Air Conditioning

Automatic Fault Detection for Big Solar Heating Systems

Fast retinal vessel analysis

A new local dimming algorithm based on the simplex method

Use of System of Systems and Decentralized Optimization Concepts for Integrated Traffic Control via Dynamic Signalization and Embedded Speed Recommendation

New frontiers in angle metrology at the PTB

The pan‐deacetylase inhibitor panobinostat suppresses the expression of oncogenic miRNAs in hepatocellular carcinoma cell lines

Agricultural trade and tropical deforestation: interactions and related policy options

Zr coordination change during crystallization of MgO–Al2O3–SiO2–ZrO2 glass ceramics

Pituitary adenylate cyclase‐activating polypeptide (PACAP) inhibits the slow afterhyperpolarizing current sI_AHP in CA1 pyramidal neurons by activating multiple signaling pathways

Mixed‐polarization phenotype of ascites‐associated macrophages in human ovarian carcinoma: Correlation of CD163 expression, cytokine levels and early relapse

Cascading Raman lasers for reducing their threshold

Unconventional reservoir potential of the upper Permian Zechstein Group: a slope to basin sequence stratigraphic and sedimentological evaluation of carbonates and organic-rich mudrocks, Northern Germany

Continuous plankton recorder underestimates zooplankton abundance

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